| Topic | Profile of the applicant | Required experience | Duration |
| Integration of a set of C routines dedicated to quantification in SPECT and PET in an medical image processing software
We have got a set of C sub-routines that allows us to build a large number of processing protocols for PET and SPECT images, including attenuation, scatter, partial volume effect corrections, and different algorithms of tomographic reconstruction. The job will consist in integrating all these routines in a user-friendly and evolutive environment including a graphical interface. |
Software engineer | Programming in C, Java
Operating systems: Linux and Unix |
3 to 6 months |
| Bootstrap in scintigraphic imaging
We have recently proposed an original approach based on the bootstrap to create multiple realizations of SPECT and PET acquisitions from a single real acquisition. We showed that this approach allowed one to study the statistical properties of reconstructed SPECT and PET images as a function of the reconstruction and image processing protocol. The project will consist in studying the value of the bootstrap approach to answer many questions relevant to the qualitative and quantitative interpretation of SPECT and PET images. |
Statistician, Mathematician, Physicist, Engineer |
|
6 month project possibly followed by a 3 year thesis |
| Iterative tomographic reconstruction in SPECT and PET
An original approach of tomographic reconstruction will be studied, that takes advantage of the latest technological advances in SPECT and PET imaging and in computing. The lack of detailed information regarding this project is only due to the condidentialty of the project. |
Statistician, Mathematician, Physicist or Engineer |
|
6 month project possibly followed by a 3 year thesis |
| High sensitivity SPECT imaging
Single Photon Emission Tomography (SPECT) has a very poor sensitivity, due to the use of a collimator that stops about 9999 out of 10,000 incoming photons. This collimator is needed to associate a direction to each photon detected in the crystal of te gamma camera. the aim of this project is ti study alterantive SPECT approach that would present amuch higher sensitivity, by modifying some basic principles of a gamma camera. |
Physicist, Engineer, Mathematician |
|
6 month project possibly followed by a 3 year thesis | Calibration for absolute quantification in SPECT
In single photon emission tomography (SPECT), a major challenge is to estimate the local concentration of radiotracer from the SPECT images. This requires a calibration procedure, which consists in establishing the relationship between signal intensity in the SPECT images and radiotracer concentration. Several empirical techniques have been proposed to reach this goal, but none of them is entirely satisfactory, in that they all perform well for a certain type of exams only (like brain scan, or heart scan, aso). The proposed project will consist in studying an alternative method that we have recently proposed, to precisely characterize its accuracy and compare the achieved accuracy with that obtained using more classical calibration approaches. | Physicist, Engineer |
|
6 month project |