Contribution to the design and validation of the GATE PET and SPECT Monte Carlo simulator


Summary Monte Carlo simulations are currently being used a lot in SPECT and PET. Indeed, they make it possible to generate realistic SPECT and PET data, while knowing exactly all the characteristics of the object being scanned, of the simulated detector and of the detected events. Using such simulations is therefore very helpful for a better understanding of SPECT and PET quantitative issues and for the evaluation of quantification procedures. There are currently about 10 different software for simulating PET or SPECT data, but most of them have been developped for some specific applications (e.g., simulating a specific camera) and have not been thoroughly validated.
This analysis therefore led the PET instrumentation group of the High Energy Physics Department at the University of Lausanne, Switzerland to develop a new generic software to simulate a wide variety of realistic SPECT and PET acquisition and detector configurations. The software is based on GEANT4, a Monte Carlo simulation software that has been developped at the CERN, and which is used a lot for research in High Energy Physics.
Our contribution to this project consists in validating the simulator in specific configurations, such as SPECT imaging with Indium 111 or F18-FDG PET in concology.
Fundings
Publications
More... The GATE project of the University of Lausanne
Connected project: Standardisation and validation of Monte Carlo simulators in Nuclear Imaging 
Other ressources regarding Monte Carlo simulations: mcnucmed Web site
Contacts Irène Buvat : buvat@imed.jussieu.fr
Karine Assié : assie@imed.jussieu.fr
Juliette Feuardent : feuarden@imed.jussieu.fr